- Street Kings (2008) …. Detective Tom Ludlow
- The Lake House (2006) …. Alex Wyler
- A Scanner Darkly (2006) …. Bob Arctor
- Constantine (2005) …. John Constantine
- Thumbsucker (2005) …. Perry Lyman
- Ellie Parker (2005) …. Dogstar
- Something’s Gotta Give (2003) …. Julian Mercer
- The Matrix Revolutions (2003) …. Neo
- Kid’s Story (2003) (voice) …. Neo
- Enter the Matrix (2003) (VG) (voice) …. Neo
- The Matrix Reloaded (2003) …. Neo
- The Animatrix (2003) (V) (voice) …. Neo (segment Kid’s Story)
- Hard Ball (2001) …. Conor O’Neill
- Sweet November (2001) …. Nelson Moss
- The Gift (2000) …. Donnie Barksdale
- The Watcher (2000/I) …. David Allen Griffin
- The Replacements (2000) …. Shane Falco
- Me and Will (1999) …. Dogstar/Himself
- The Matrix (1999) …. Neo
- The Devil’s Advocate (1997) …. Kevin Lomax
- The Last Time I Committed Suicide (1997) …. Harry
- Feeling Minnesota (1996) …. Jjaks Clayton
- Chain Reaction (1996) …. Eddie Kasalivich
- A Walk in the Clouds (1995) …. Paul Sutton
- Johnny Mnemonic (1995) …. Johnny Mnemonic
- Speed (1994/I) …. Officer Jack Traven
- Little Buddha (1993) …. Siddhartha
- Even Cowgirls Get the Blues (1993) …. Julian Gitche
- Freaked (1993) (uncredited) …. Ortiz the Dog Boy
- Much Ado About Nothing (1993) …. Don John
- Dracula (1992) …. Jonathan Harker
- My Own Private Idaho (1991) …. Scott Favor
- Bill & Ted’s Bogus Journey (1991) …. Ted Logan / Evil Ted
- Point Break (1991) …. FBI Special Agent John ‘Johnny’ Utah
- Captivated ‘92: The Video Collection (1991) (V) …. Jeff (segment Rush, Rush)
- Providence (1991) …. Eric
- Tune in Tomorrow… (1990) …. Martin Loader
- I Love You to Death (1990) …. Marlon James
- Bill & Ted’s Excellent Adventures …. Ted Logan (1 episode, 1990)
- The Tracey Ullman Show …. Jesse Walker (1 episode, 1989)
- Parenthood (1989) …. Tod Higgins
- Bill & Ted’s Excellent Adventure (1989) …. Ted Logan
- Life Under Water (1989) (TV) …. Kip
- Dangerous Liaisons (1988) …. Le Chevalier Raphael Danceny
- The Prince of Pennsylvania (1988) …. Rupert Marshetta
- Permanent Record (1988) …. Chris Townsend
- The Night Before (1988) …. Winston Connelly
- Trying Times …. Joey (1 episode, 1987)
- Babes in Toyland (1986) (TV) …. Jack/Jack-be-Nimble
- Under the Influence (1986) (TV) …. Eddie Talbot
- River’s Edge (1986) …. Matt
- The Brotherhood of Justice (1986) (TV) …. Derek
- Young Again (1986) (TV) (as K.C. Reeves) …. Michael Riley, Age 17
- Act of Vengeance (1986) (TV) (as Keannu Reeves) …. Buddy Martin
- Youngblood (1986) …. Heaver
- Flying (1986) …. Tommy
- One Step Away (1985) …. Ron Petrie
- Comedy Factory …. Crackers (1 episode, 1985)
- Letting Go (1985) (TV) …. Stereo Teen #1
- Night Heat …. Mugger / … (2 episodes, 1985)
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